NASA eClips are short, relevant educational video segments that inspire and engage students, helping them see real-world connections. New video segments are produced weekly exploring current applications of science, technology, engineering, and mathematics - or "STEM" - topics. The programs are produced for targeted audience groups K-5, 6-8, 9-12 and the general public.

NASA eClips offer unlimited flexibility in the classroom for timing, sequencing, and pacing instruction to meet the needs of students and classroom instructors. The website also offers a variety of other teaching materials such as images, maps, and games.

Educational material for this program is selected based on national curriculum standards identified by the National Council of Teachers of Mathematics (NCTM), the National Science Teachers Association (NSTA), the International Society for Technology in Education (ISTA), and Project 2061. Project 2061 is a nationwide initiative to ensure that all high-school graduates are science literate.